Impact of Physical Activity on Reducing Blood Glucose and Insulin in Gestational Diabetes: A Meta-Analysis
top of page
Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute
Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute

Journal of Health and Medical Sciences

ISSN 2622-7258

Screen Shot 2018-08-12 at 1.24.09 AM.png
Screen Shot 2018-08-12 at 1.24.02 AM.png
Screen Shot 2018-08-12 at 1.23.57 AM.png
Screen Shot 2018-08-12 at 1.23.52 AM.png
crossref
doi
open access

Published: 01 December 2024

Impact of Physical Activity on Reducing Blood Glucose and Insulin in Gestational Diabetes: A Meta-Analysis

Fitrawan Alfiansyah, Dian A. R. Dewi, Gede B. N. K. T. Susila, Aryoga K. Murti, Lila I. T. Widuri, Rosalia Sylfiasari, Farida Ulfa, Annisa Ramadhanti, Thalia A. Elsiyana

Indonesia Defense University (Indonesia), Atma Jaya Catholic University (Indonesia), Pembangunan Nasional ‘Veteran’ University (Indonesia), Padjajaran University (Indonesia), Sebelas Maret University (Indonesia)

journal of social and political sciences
pdf download

Download Full-Text Pdf

doi

10.31014/aior.1994.07.04.331

Pages: 79-88

Keywords: Fasting Blood Glucose Level, Gestational Diabetes Mellitus, Insulin, Physical Activity, Postprandial Glucose Level

Abstract

Gestational diabetes mellitus is a pregnancy complication characterized by elevated blood glucose levels, which can affect the health of both the mother and fetus. This study aims to evaluate the impact of physical exercise on blood glucose levels in pregnant women with gestational diabetes mellitus. We reviewed studies published over the past ten years from PubMed, Cochrane, and Science Direct. Our analysis includes randomized controlled trials exploring the role of physical activity in blood glucose management among gestational diabetes mellitus patients, examining both aerobic and anaerobic exercise interventions. We extracted data on maternal characteristics, intervention details, and outcomes post-intervention. Fasting and postprandial blood glucose levels were our primary results. Diabetes mellitus is a complication during pregnancy marked by high blood glucose levels, which can impact both the mother and the unborn child. This study finds that physical exercise positively influences metabolism in women with gestational diabetes mellitus, particularly in controlling and reducing blood glucose levels. Exercise significantly affected postprandial blood glucose levels.

References

  1. ACOG Practice Bulletins. (2018). Gestational diabetes mellitus. ACOG Practice Bulletin No. 190. American College of Obstetricians and Gynecologists. Obstetrics and Gynecology, 131(180), e49–e64.

  2. Andersen, M. B., Fuglsang, J., Ostenfeld, E. B., Poulsen, C. W., Daugaard, M., & Ovesen, P. G. (2021). Postprandial interval walking—effect on blood glucose in pregnant women with gestational diabetes. American Journal of Obstetrics and Gynecology MFM, 3(6), 100440. https://doi.org/10.1016/j.ajogmf.2021.100440

  3. Beyuo, T., Obed, S. A., Adjepong-Yamoah, K. K., Bugyei, K. A., Oppong, S. A., & Marfoh, K. (2015). Metformin versus insulin in the management of pre-gestational diabetes mellitus in pregnancy and gestational diabetes mellitus at the Korle Bu Teaching Hospital:A randomized clinical trial. PLoS ONE, 10(5), 1–10. https://doi.org/10.1371/journal.pone.0125712

  4. Bo, S., Rosato, R., Ciccone, G., Canil, S., Gambino, R., Poala, C. B., Leone, F., Valla, A., Grassi, G., Ghigo, E., Cassader, M., & Menato, G. (2014). Simple lifestyle recommendations and the outcomes of gestational diabetes. A 2×2 factorial randomized trial. Diabetes, Obesity and Metabolism, 16(10), 1032–1035. https://doi.org/10.1111/dom.12289

  5. Chiefari, E., Arcidiacono, B., Foti, D., & Brunetti, A. (2017). Gestational diabetes mellitus: an updated overview. Journal of Endocrinological Investigation, 40(9), 899–909. https://doi.org/10.1007/s40618-016-0607-5

  6. Dawn Coe, Scott Conger, Jo Kendrick, Bobby Howard, Dixie Thompson, David Bassett, J. W. (2017). Postprandial Walking Reduces Glucose Levels in Women with Gestational Diabetes Mellitus. Applied Physiology, Nutrition, and Metabolism.

  7. do Nascimento, G. R., Borges, M. do C., Figueiroa, J. N., Alves, L. V., & Alves, J. G. (2019). Physical activity pattern in early pregnancy and gestational diabetes mellitus risk among low-income women: A prospective cross-sectional study. SAGE Open Medicine, 7. https://doi.org/10.1177/2050312119875922

  8. Embaby, H., Elsayed, E., & Fawzy, M. (2016). Insulin Sensitivity and Plasma Glucose Response to Aerobic Exercise in Pregnant Women at Risk for Gestational Diabetes Mellitus. Ethiopian Journal of Health Sciences, 26(5), 409–414. https://doi.org/10.4314/ejhs.v26i5.2

  9. Gu, C., He, G., & Lin, C. (2022). Evaluation of High Levels of Sports Activity and the Beneficial Effect on Postprandial Blood Glucose Profiles. Revista Brasileira de Medicina Do Esporte, 28(5), 465–468. https://doi.org/10.1590/1517-8692202228052022_127

  10. Hamidreza Sheikhi, Mojtaba Jahromi, Alireza Sheikhi, hadis M. (2017). The Effect of Physical Activity Training Through Focused Group Discussions on Fasting Blood Glucose Level on Pregnant Women with Gestational Diabetes. Revista QUID, 2830–2834.

  11. Hegde, B. M. (2018). Health benefits of exercise. Kuwait Medical Journal, 50(2), 143–145. https://doi.org/10.1249/01.mss.0000477455.85942.2f

  12. Kim, K. S., Hong, S., Han, K., & Park, C. Y. (2021). The Clinical Characteristics of Gestational Diabetes Mellitus in Korea: A National Health Information Database Study. Endocrinology and Metabolism, 36(3), 628–636. https://doi.org/10.3803/ENM.2020.948

  13. Ko, K. J., Kim, E. H., Baek, U. H., Gang, Z., & Kang, S. J. (2016). The relationship between physical activity levels and metabolic syndrome in male white-collar workers. Journal of Physical Therapy Science, 28(11), 3041–3046. https://doi.org/10.1589/jpts.28.3041

  14. Kodikonda, M., & Naik, P. R. (2017). Ameliorative effect of borneol, a natural bycyclic monoterpene against hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic Wistar rats. Biomedicine and Pharmacotherapy, 96(September), 336–347. https://doi.org/10.1016/j.biopha.2017.09.122

  15. Kouhkan, A., Najafi, L., Malek, M., Baradaran, H. R., Hosseini, R., Khajavi, A., & Khamseh, M. E. (2021). Gestational diabetes mellitus: Major risk factors and pregnancy-related outcomes: A cohort study. International Journal of Reproductive BioMedicine, 19(9), 827–836. https://doi.org/10.18502/ijrm.v19i9.9715

  16. Laredo-Aguilera, J. A., Gallardo-Bravo, M., Rabanales-Sotos, J. A., Cobo-Cuenca, A. I., & Carmona-Torres, J. M. (2020). Physical activity programs during pregnancy are effective for the control of gestational diabetes mellitus. International Journal of Environmental Research and Public Health, 17(17), 1–14. https://doi.org/10.3390/ijerph17176151

  17. Leng, J., Liu, G., Zhang, C., Xin, S., Chen, F., Li, B., Tian, H., Yu, Z., Tuomilehto, J., Hu, G., & Yang, X. (2016). Physical activity, sedentary behaviors and risk of gestational diabetes mellitus: A population-based cross-sectional study in Tianjin, China. European Journal of Endocrinology, 174(6), 763–773. https://doi.org/10.1530/EJE-15-1103

  18. Ming, W. K., Ding, W., Zhang, C. J. P., Zhong, L., Long, Y., Li, Z., Sun, C., Wu, Y., Chen, H., Chen, H., & Wang, Z. (2018). The effect of exercise during pregnancy on gestational diabetes mellitus in normal-weight women: A systematic review and meta-analysis. BMC Pregnancy and Childbirth, 18(1), 1–9. https://doi.org/10.1186/s12884-018-2068-7

  19. Mottola, M. F., & Artal, R. (2016). Role of exercise in reducing gestational diabetes mellitus. Clinical Obstetrics and Gynecology, 59(3), 620–628. https://doi.org/10.1097/GRF.0000000000000211

  20. Murphy, H. R., Bell, R., Cartwright, C., Curnow, P., Maresh, M., Morgan, M., Sylvester, C., Young, B., & Lewis-Barned, N. (2017). Improved pregnancy outcomes in women with type 1 and type 2 diabetes but substantial clinic-to-clinic variations: a prospective nationwide study. Diabetologia, 60(9), 1668–1677. https://doi.org/10.1007/s00125-017-4314-3

  21. Ozougwu, O. (2013). The pathogenesis and pathophysiology of type 1 and type 2 diabetes mellitus. Journal of Physiology and Pathophysiology, 4(4), 46–57. https://doi.org/10.5897/jpap2013.0001

  22. Sklempe Kokic, I., Ivanisevic, M., Kokic, T., Simunic, B., & Pisot, R. (2018). Acute responses to structured aerobic and resistance exercise in women with gestational diabetes mellitus. Scandinavian Journal of Medicine and Science in Sports, 28(7), 1793–1800. https://doi.org/10.1111/sms.13076

  23. Sklempe Kokic, Iva, Ivanisevic, M., Biolo, G., Simunic, B., Kokic, T., & Pisot, R. (2018). Combination of a structured aerobic and resistance exercise improves glycaemic control in pregnant women diagnosed with gestational diabetes mellitus. A randomised controlled trial. Women and Birth, 31(4), e232–e238. https://doi.org/10.1016/j.wombi.2017.10.004

  24. Wang, C., Guelfi, K. J., & Yang, H. (2016). Exercise and its role in gestational diabetes mellitus. Chronic Diseases and Translational Medicine, 2(4), 208–214. https://doi.org/10.1016/j.cdtm.2016.11.006

  25. Woodside, A., & Bradford, H. (2021). Exercise and the Prevention of Gestational Diabetes Mellitus. Nursing for Women’s Health, 25(4), 304–311. https://doi.org/10.1016/j.nwh.2021.05.009

  26. Xia, Z., Jiang, Y. Y., Shang, W. J., Guo, H. J., Mao, F., Dong, W. L., & Dong, J. Q. (2021). Long-term effectiveness of group-based diabetes self-management on glycosylated haemoglobin for people with type 2 diabetes in community: a protocol of systematic review and meta-analysis. BMJ Open, 11(6), 1–7. https://doi.org/10.1136/bmjopen-2020-046692

  27. Xie, Y., Zhao, H., Zhao, M., Huang, H., Liu, C., Huang, F., & Wu, J. (2022). Effects of resistance exercise on blood glucose level and pregnancy outcome in patients with gestational diabetes mellitus: A randomized controlled trial. BMJ Open Diabetes Research and Care, 10(2), 1–10. https://doi.org/10.1136/bmjdrc-2021-002622

  28. Youngwanichsetha, S., Phumdoung, S., & Ingkathawornwong, T. (2014). The effects of mindfulness eating and yoga exercise on blood sugar levels of pregnant women with gestational diabetes mellitus. Applied Nursing Research, 27(4), 227–230. https://doi.org/10.1016/j.apnr.2014.02.002

  29. Zhu, Y., Zhang, C., & Kennedy, E. (2019). Prevalence of Gestational Diabetes and Risk of Progression to Type 2 Diabetes: a Global Perspective. Current Diabetes, 16(1), 1–19. https://doi.org/10.1007/s11892-015-0699-x.Prevalence

bottom of page