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Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute
Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute

Journal of Health and Medical Sciences

ISSN 2622-7258

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open access

Published: 20 December 2023

Minimally Invasive Thoracoscopic Surgery of Lung Adenocarcinoma in Old Age People

Sadam Hussain, Amna Abbasi, Li-Wei Zhang, Julaiti Ainiwaer

Xinjiang Medical University, Hospital of Xinjiang Medical University

journal of social and political sciences
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doi

10.31014/aior.1994.06.04.296

Pages: 229-236

Keywords: Video-Assisted Thoracoscopic Surgery (VATS), Lung Adenocarcinoma and Minimally Invasive Surgery

Abstract

Background: Lung cancer is the most frequent human malignancy and the principal cause of cancer-related death worldwide. Adenocarcinoma is now the main histologic type, accounting for almost half of all the cases. Lung cancer is the leading cause of cancer-related death in most developed countries. Over the last 50 years, the prevalence of adenocarcinoma has been increasing comparative to other lung cancer subtypes. Objective: To determine Minimally invasive thoracoscopic surgery of lung adenocarcinoma in old age. Methods: A cross-sectional study was conducted at Shifa International hospital Islamabad Pakistan, which was performed between April 2020 and January 2022. The total number of patients in our study was 152. The number of Male patients was 62 and female were 90. In 152 consecutive patients who underwent for CT guided biopsy, the needle was used 18 Guage. We diagnosed the Lung adenocarcinoma of all patients on CT scan. The age of all patients was more than 40 years. We took in our study stage (1A) of lung adenocarcinoma, which has further 3 subtypes 1A1,1A2 and 1A3. The size of Stage 1A1 up to 1 cm, Stage 1A2 >1 cm <2cm and stage 1A3 >2cm <3cm. We did for all patients Video-assisted thoracoscopic surgery. The surgeon makes one to five small incisions, each one an about 1 inch in between two ribs. Data was tabulated and analyzed by SPSS. Results: The stage of lung adenocarcinoma 1A1 in male patients were 17 and female were 31. The stage of lung adenocarcinoma 1A2 in male patients were 29 and female were 37. The stage of lung adenocarcinoma 1A3 in male patients were 16 and female were 22. Total male patients were 62 and females were 90. P-value of stages of lung adenocarcinoma in gender was 0.64. The stage of lung adenocarcinoma in the age group of 40-50 years 1A1 were 8, 1A2 were 7 and 1A3 were 2. The total patients with age 40-50 years were 17. The stage of lung adenocarcinoma in the age group of 51-65 years 1A1 were 34, 1A2 were 48 and 1A3 were 19. The total patients with age 51-65 years were 101. The stage of lung adenocarcinoma in the age group of >66 years 1A1 was 6, 1A2 was 11 and 1A3 was 17. The total patients with age >66 years was 34. P-value of stages of lung adenocarcinoma in age group was 0.003. The minimum patient recovery time was 3 weeks and the maximum patient recovery time was 5 weeks. The minimum age group of patient was 43 and the maximum age group of patients was 77. MEAN±SD of age was 59.67±7.85. Conclusion: Video-assisted thoracoscopic surgery (VATS) is a reliable and safe approach for the diagnosis and treatment of lung adenocarcinoma with a low complication rate. Minimally invasive techniques are even more advantageous among the elderly. The patient recovery time from 3 weeks to 5 weeks. The frequency of lung adenocarcinoma is more common in the upper lobe as compare to other lobes. In our study, the prognosis of VATS was better than Open Surgery because the patient's recovery time was less than the open surgery procedure.

References

  1. Abouarab, A. A., Rahouma, M., Kamel, M., Ghaly, G., & Mohamed, A. (2018). Single Versus Multi-Incisional Video-Assisted Thoracic Surgery: A Systematic Review and Meta-analysis. Journal of laparoendoscopic & advanced surgical techniques. Part A, 28(2), 174–185. https://doi.org/10.1089/lap.2017.0446

  2. Augustin, F., Maier, H., Lucciarini, P., Bodner, J., Klotzner, S., & Schmid, T. (2016). Extended minimally invasive lung resections: VATS bilobectomy, bronchoplasty, and pneumonectomy. Langenbeck's archives of surgery, 401(3), 341–348. https://doi.org/10.1007/s00423-015-1345-4

  3. Agasthian T. (2013). Initial experience with video-assisted thoracoscopic bronchoplasty. European journal of cardio-thoracic surgery: official journal of the European Association for Cardio-thoracic Surgery, 44(4), 616–623. https://doi.org/10.1093/ejcts/ezt166

  4. Cao, M., & Chen, W. (2019). Epidemiology of lung cancer in China. Thoracic cancer, 10(1), 3–7. https://doi.org/10.1111/1759-7714.12916

  5. Dziedzic, D., & Orlowski, T. (2015). The Role of VATS in Lung Cancer Surgery: Current Status and Prospects for Development. Minimally invasive surgery, 2015, 938430. https://doi.org/10.1155/2015/938430

  6. Dumitra, T. C., Molina, J. C., Mouhanna, J., Nicolau, I., Renaud, S., Aubin, L., Siblini, A., Mulder, D., Ferri, L., & Spicer, J. (2020). Feasibility analysis for the development of a video-assisted thoracoscopic (VATS) lobectomy 23-hour recovery pathway. Canadian journal of surgery. Journal canadien de chirurgie, 63(4), E349–E358. https://doi.org/10.1503/cjs.002219.

  7. Klapper, J., & D'Amico, T. A. (2015). VATS versus open surgery for lung cancer resection: moving toward a minimally invasive approach. Journal of the National Comprehensive Cancer Network: JNCCN, 13(2), 162–164. https://doi.org/10.6004/jnccn.2015.0023

  8. Gonfiotti, A., Viggiano, D., Voltolini, L., Bertani, A., Bertolaccini, L., Crisci, R., & Droghetti, A. (2018). Enhanced recovery after surgery and video-assisted thoracic surgery lobectomy: the Italian VATS Group surgical protocol. Journal of thoracic disease, 10(Suppl 4), S564–S570. https://doi.org/10.21037/jtd.2018.01.157

  9. Gill, R. R., Zheng, Y., Barlow, J. S., Jayender, J., Girard, E. E., Hartigan, P. M., Chirieac, L. R., Belle-King, C. J., Murray, K., Sears, C., Wee, J. O., Jaklitsch, M. T., Colson, Y. L., & Bueno, R. (2015). Image-guided video assisted thoracoscopic surgery (iVATS) - phase I-II clinical trial. Journal of surgical oncology, 112(1), 18–25. https://doi.org/10.1002/jso.23941

  10. Hutchinson, B. D., Shroff, G. S., Truong, M. T., & Ko, J. P. (2019). Spectrum of Lung Adenocarcinoma. Seminars in ultrasound, CT, and MR, 40(3), 255–264. https://doi.org/10.1053/j.sult.2018.11.009

  11. Hsin, M. K., & Yim, A. P. (2010). Management of complications of minimally invasive thoracic surgery. Respirology (Carlton, Vic.), 15(1), 6–18. https://doi.org/10.1111/j.1440-1843.2009.01653.x

  12. Imperatori, A., Rotolo, N., Gatti, M., Nardecchia, E., De Monte, L., Conti, V., & Dominioni, L. (2008). Peri-operative complications of video-assisted thoracoscopic surgery (VATS). International journal of surgery (London, England), 6 Suppl 1, S78–S81. https://doi.org/10.1016/j.ijsu.2008.12.014

  13. Jiang, L., Lei, T., Zhou, K., Ma, H., & Che, G. (2021). Pivotal role of video-assisted thoracoscopic surgery in improving survival outcome of stage I non-small cell lung cancer in day surgery patients. Thoracic cancer, 12(21), 2865–2872. https://doi.org/10.1111/1759-7714.14145

  14. Nooreldeen, R., & Bach, H. (2021). Current and Future Development in Lung Cancer Diagnosis. International journal of molecular sciences, 22(16), 8661. https://doi.org/10.3390/ijms22168661

  15. Klapper, J., & D'Amico, T. A. (2015). VATS versus open surgery for lung cancer resection: moving toward a minimally invasive approach. Journal of the National Comprehensive Cancer Network: JNCCN, 13(2), 162–164. https://doi.org/10.6004/jnccn.2015.0023

  16. Lemjabbar-Alaoui, H., Hassan, O. U., Yang, Y. W., & Buchanan, P. (2015). Lung cancer: Biology and treatment options. Biochimica et biophysica acta, 1856(2), 189–210. https://doi.org/10.1016/j.bbcan.2015.08.002

  17. Lim, W., Ridge, C. A., Nicholson, A. G., & Mirsadraee, S. (2018). The 8th lung cancer TNM classification and clinical staging system: review of the changes and clinical implications. Quantitative imaging in medicine and surgery, 8(7), 709–718. https://doi.org/10.21037/qims.2018.08.02

  18. McLean, A. E. B., Barnes, D. J., & Troy, L. K. (2018). Diagnosing Lung Cancer: The Complexities of Obtaining a Tissue Diagnosis in the Era of Minimally Invasive and Personalised Medicine. Journal of clinical medicine, 7(7), 163. https://doi.org/10.3390/jcm7070163

  19. Myers, D. J., & Wallen, J. M. (2023). Lung adenocarcinoma. In StatPearls [Internet]. StatPearls Publishing.

  20. Nakamura, H., & Saji, H. (2014). Worldwide trend of increasing primary adenocarcinoma of the lung. Surgery today, 44(6), 1004–1012. https://doi.org/10.1007/s00595-013-0636-z

  21. Nooreldeen, R., & Bach, H. (2021). Current and Future Development in Lung Cancer Diagnosis. International journal of molecular sciences, 22(16), 8661. https://doi.org/10.3390/ijms22168661

  22. Ogawa, H., Uchino, K., Tanaka, Y., Shimizu, N., Okuda, Y., Tane, K., Hokka, D., Tane, S., Tauchi, S., Nishio, W., Maniwa, Y., & Yoshimura, M. (2015). Outcomes of segmentectomy for cT1bN0M0 lung adenocarcinoma and squamous cell carcinoma: a possible association with pathological invasion. European journal of cardio-thoracic surgery: official journal of the European Association for Cardio-thoracic Surgery, 48(1), 77–82. https://doi.org/10.1093/ejcts/ezu429

  23. Sheikh, H. S., Munawar, K., Sheikh, F., & Qamar, M. F. U. (2022). Lung Cancer in Pakistan. Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer, 17(5), 602–607. https://doi.org/10.1016/j.jtho.2022.01.009

  24. Sakurai, H., Asamura, H., Miyaoka, E., Yoshino, I., Fujii, Y., Nakanishi, Y., Eguchi, K., Mori, M., Sawabata, N., Okumura, M., Yokoi, K., & Japanese Joint Committee of Lung Cancer Registry (2014). Differences in the prognosis of resected lung adenocarcinoma according to the histological subtype: a retrospective analysis of Japanese lung cancer registry data. European journal of cardio-thoracic surgery: official journal of the European Association for Cardio-thoracic Surgery, 45(1), 100–107. https://doi.org/10.1093/ejcts/ezt284

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