top of page
Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute
Asian Institute of Research, Journal Publication, Journal Academics, Education Journal, Asian Institute

Journal of Health and Medical Sciences

ISSN 2622-7258

Screen Shot 2018-08-12 at 1.24.09 AM.png
Screen Shot 2018-08-12 at 1.24.02 AM.png
Screen Shot 2018-08-12 at 1.23.57 AM.png
Screen Shot 2018-08-12 at 1.23.52 AM.png
crossref
doi
open access

Published: 06 March 2023

Acute Transverse Myelitis as a Neurologic Complication in an Asymptomatic COVID-19 patient

Philip Rico P. Mejia, Valmarie S. Estrada

Cardinal Santos Medical Center (Philippines), University of the East Ramon Magsaysay Memorial Medical Center (Philippines)

journal of social and political sciences
pdf download

Download Full-Text Pdf

doi

10.31014/aior.1994.06.01.256

Pages: 34-39

Keywords: Asymptomatic Patient, Covid-19, Transverse Myelitis, Case Report

Abstract

We report a case of a female presenting with sudden onset of bilateral lower extremity weakness and hyperesthesia and was managed as case of acute transverse myelitis. Diagnostics such as CSF analysis, autoimmune and infectious workups were unremarkable. However, patient tested positive for COVID-19 incidentally since she didn’t present any COVID-19-related pulmonary or systemic symptoms. Thoracolumbosacral spine Magnetic resonance imaging revealed longitudinally extensive transverse myelitis. She was then administered with intravenous methylprednisolone pulse therapy and underwent extensive physical rehabilitation with marked improvement during outpatient follow-up.

References

  1. Ahmed, J. O., Ahmad, S. A., Hassan, M. N., Kakamad, F. H., Salih, R. Q., Abdulla, B. A., Rahim Fattah, F. H., Mohammed, S. H., Ali, R. K., & Salih, A. M. (2022). Post COVID-19 neurological complications; a meta-analysis. Annals of Medicine and Surgery, 76, 103440. https://doi.org/https://doi.org/10.1016/j.amsu.2022.103440

  2. Bauer, L., Laksono, B. M., de Vrij, F. M. S., Kushner, S. A., Harschnitz, O., & van Riel, D. (2022). The neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2. Trends in Neurosciences, 45(5), 358–368. https://doi.org/10.1016/j.tins.2022.02.006

  3. Beh, S. C., Greenberg, B. M., Frohman, T., & Frohman, E. M. (2013). Transverse Myelitis. Neurologic Clinics, 31(1), 79–138. https://doi.org/https://doi.org/10.1016/j.ncl.2012.09.008

  4. Gulati, N., Kapila, S., Bhalla Sehgal, L., Sehgal, V., & LNU, P. (2022). Myelitis Following COVID-19 Illness. Cureus, 14(8), e28134. https://doi.org/10.7759/cureus.28134

  5. Gupta, A., Madhavan, M. v, Sehgal, K., Nair, N., Mahajan, S., Sehrawat, T. S., Bikdeli, B., Ahluwalia, N., Ausiello, J. C., Wan, E. Y., Freedberg, D. E., Kirtane, A. J., Parikh, S. A., Maurer, M. S., Nordvig, A. S., Accili, D., Bathon, J. M., Mohan, S., Bauer, K. A., … Landry, D. W. (2020). Extrapulmonary manifestations of COVID-19. Nature Medicine, 26(7), 1017–1032. https://doi.org/10.1038/s41591-020-0968-3

  6. Lingas, E. C. (2022). A Case of Acute Transverse Myelitis in a Mildly Symptomatic Patient: An Emerging and Serious Neurological Manifestation of COVID-19. Cureus. https://doi.org/10.7759/cureus.24222

  7. Qazi, R., Memon, A., Mohamed, A. S., Ali, M., & Singh, R. (2021). Post-COVID-19 Acute Transverse Myelitis: A Case Report and Literature Review. Cureus, 13(12), e20628. https://doi.org/10.7759/cureus.20628

  8. Quiles, L. E. P., Tiongson, J. J. A., Buensalido, M. J. O. v., & Buensalido, M. B. (2022). Transverse myelitis as neurologic sequelae in a COVID-19 recovered patient. Neuroimmunology Reports, 2, 100055. https://doi.org/10.1016/j.nerep.2022.100055

  9. Román, G. C., Gracia, F., Torres, A., Palacios, A., Gracia, K., & Harris, D. (2021). Acute Transverse Myelitis (ATM):Clinical Review of 43 Patients With COVID-19-Associated ATM and 3 Post-Vaccination ATM Serious Adverse Events With the ChAdOx1 nCoV-19 Vaccine (AZD1222). Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.653786

  10. Schulte, E. C., Hauer, L., Kunz, A. B., & Sellner, J. (2021). Systematic review of cases of acute myelitis in individuals with COVID‐19. European Journal of Neurology, 28(10), 3230–3244. https://doi.org/10.1111/ene.14952

  11. Vasconcelos, T. de M. F., Oliveira, D. N., Ferreira, G. de M., Torres, F. C., Castro, J. D. V. de, Braga-Neto, P., & Sobreira-Neto, M. A. (2021). Covid-19 post-infectious acute transverse myelitis responsive to corticosteroid therapy: report of two clinical cases. Journal of NeuroVirology, 27(5), 791–796. https://doi.org/10.1007/s13365-021-01010-x

bottom of page